Fig. 8. Effect of SFN on the As induced changes in the histology of liver in the control and experimental animals (A-E). (A) Control rats: Normal liver tissue histology is seen (40x). (B&C) As treated rats showed degenerative changes, such as degeneration of hepatocytes with necrosis (NEC), inflammation (INF), vacuolization (VC), inflammatory cell infiltration (ICI) and sinusoidal dilation (SD) (40x). (D) As treated rats with SFN: Effective preventing of degenerative changes and shrunken in cytoplasm and nuclei are prominent in liver cells (40x). (E) SFN alone treated rats: Although similar liver tissue histology was observed compared to control (40x). (H&E 40x).